Gene Linkage and Human Genome Project
Reading ?’s 7.4– Due Wed, Feb 21st
Review (see below)- Due Fri, Feb 23rd
Pedigree Project (see guidelines below)- Due Thurs, Feb 22nd
Genetics Test- Fri, Feb 23rd
Performance Task #2
Goal: Create a pedigree of at least three generations, including at least seven family members, demonstrating the inheritance of a simple inheritance human genetic trait to an interested family.
Audience: Your target audience is family who wishes to know about their inheritance patterns. (This could be your own family or that of a friend or acquaintance.)
Possible Traits to Study: Cleft chin (dimple in the chin); Facial dimples; Attachment of the ear lobe; Facial freckles; Hitchhiker’s thumb; Widow’s Peak
- Interview family members to identify what phenotype each member has.
- Using the phenotypes over the three generations to identify genotypes. Use Punnett squares and written explanation for your evidence for the identification of genotypes.
- Using this information, draw a pedigree, using the correct symbols, to show the inheritance of the selected trait in this family.
|Identification of Genotypes|
|Major Errors||Minor Error(s)||Well-Done|
|Phenotypes match to the identified genotypes||There are more than 3 individuals in the pedigree whose phenotypes do not match the correct genotype||One or two individuals in the pedigree whose phenotypes do not match the correct genotype||All phenotypes match genotypes accurately|
|Punnett squares||Punnett square inaccurately display the inheritance patterns by which the traits were passed from one generation to the next||Punnett squares demonstrate the inheritance patterns by which the traits were passed from one generation to the next, with one or two errors.||All Punnett square accurately demonstrate the inheritance patterns by which the traits were passed from one generation to the next|
|Written explanation||Written explanation does not provide details about the identification of genotypes OR the explanation reveals major errors in the identification of genotypes||Written explanation gives a detailed, accurate description of the identification of the genotype of most individuals on the pedigree OR the explanations fails to fully detail the identification of accurate genotypes||Written explanation gives a detailed, accurate description of the identification of the genotype of all individuals on the pedigree
|Major Errors||Minor Error(s)||Well-Done|
|Inheritance Display||The pedigree displays how one trait is passed through the three generations, but with errors in multiple generations.||The pedigree displays how one trait is passed through the three generations, but with an error in one of the three generations.||The pedigree accurately displays how one trait is passed through the three generations.|
|Symbols||Symbols for males, females, displaying trait, carrier, and non-displaying are used, with three or more errors||Symbols for males, females, displaying trait, carrier, and non-displaying are used, with one or two errors||Correct symbols for males, females, displaying trait, carrier, and non-displaying are used|
Ch.6 & 7
- State Mendel’s three laws of inheritance
- Explain how Mendel performed his experiments. (mention P, F1 and F2 generations)
- What were the results of each of Mendel’s experiments? (F1 and F2 generations)
- Define pedigree, complete dominance, incomplete dominance, codominance, phenotype, genotype, dominant, recessive, testcross, X-linked, allele, heterozygous, and homozygous.
- When dealing with a completely dominant trait, under what conditions can a recessive trait appear?
- Why do males more often have a X-linked recessive phenotype than females?
- Describe how the following human traits are inherited: blood type, hair texture, color blindness, brown or blue eye color, and hemophilia
- Draw a simple pedigree, showing the following a male with a trait and a female without the trait have a carrier female child and a child who does not have the trait. Label the following: symbol for male, symbol for female, indicates that it has the trait, indicates that it is without the trait, indicates marriage, indicates offspring, and indicates siblings.
- Describe what are linked genes and how this impacts their inheritance
**Review your Punnett square and pedigree practice worksheets. You should know how to complete Punnett squares for complete dominance, incomplete dominance, codominance, multiple alleles, X-linked, and two factor crosses. You should be able to derive the parents’ genotypes based on their offspring. You should also be able to interpret a pedigree.